HOST-MICROBE COMPUTATIONAL PROTEOMIC LANDSCAPE IN ORAL CANCER REVEALED KEY FUNCTIONAL AND METABOLIC PATHWAYS BETWEEN FUSOBACTERIUM NUCLEATUM AND CANCER PROGRESSION

Abstract Oral squamous cell carcinoma (OSCC) is the most common manifestation of oral cancer.It has been proposed that periodontal pathogens contribute to OSCC progression, mainly by their virulence factors.However, the main periodontal pathogen and its mechanism to modulate OSCC cells remains not fully understood.In this study we investigate the m

Abstract Background Keratoconus is a common disease in clinical practice, and deep anterior lamellar keratoplasty(DALK) is a conventional treatment for keratoconus, which is effective and not easy to recur after surgery.Case Fridge Crisper Shelf Attachment presentation The author presents a rare case report involving a 21-year-old patient with Cons

Protein characterization highly depends on its operating conditions, where native or often referred as non-denaturing options will greatly facilitate the collection of more biologically meaningful information.Native mass spectrometry (MS) is such a technique that enables protein analysis under non-denaturing conditions with an affordable time and s

Muscle strength and physical function decrease in older men, as do testosterone levels.Nonetheless, the effects of testosterone replacement therapy on muscle strength and physical function remain inconclusive and Mice and Keyboard Sets equivocal.We conducted a rapid systematic review, the results of which showed that testosterone replacement does n

Severe spinal cord injuries (SCIs) usually result in the temporary or permanent impairment of strength, sensation or autonomic functions below the sites of injuries.To date, a large number of therapeutic approaches have been used to ameliorate SCIs, and subsequent stem cell transplantation appears to be a promising strategy.The aim of this study wa